Celebrating over 30 years of independent research
Medical Technology & Practice Patterns Institute (MTPPI) is a nonprofit organization established in 1986 to conduct research on the clinical and economic implications of health care technologies. MTPPI’s research is directed toward the formulation and implementation of local and national health care policies.
With extensive investigator experience in both the public and private sectors, MTPPI’s staff designs, implements, and conducts a full range of healthcare research and technology development activities. Our staff includes statisticians, epidemiologists, economists, programmers, biomedical engineers, and policy analysts. We specialize in using big data to conduct “real-time”, “real-world” studies that are both affordable and useful for healthcare stakeholders.
“By enhancing the methods for conducting Comparative Effectiveness Research, MTPPI will provide information that will ultimately help people make more fully informed health and healthcare decisions.”
Board of Directors
- Tom Keon, President of Ridgewells Inc.
Dr. Andrew Narva, Director of NKDEP (retired)
- Dr. Lawrence Friedman, NHLBI (retired).
Dennis Cotter, President of MTPPI
MTPPI Senior Leadership

The Grant Perry Memorial Library
The Medical Technology and Practice Patterns Institute has established The Grant Perry Memorial Library to honor the legacy of former Board Director Grant Perry. Mr. Perry was a fierce patient advocate in addition to being a respected journalist, writer, and lawyer. To support his patient advocacy initiatives, Mr. Perry founded PatientPilot, a 501(c)(3) charitable and educational organization that creates educational technology and materials that “coach” patients on what questions to ask their doctors. In addition to being a valuable Director for MTPPI’s Board, Mr. Perry served on the board of Friends of Patients at the NIH and was a member of the Patient Advisory Group to the CEO of the NIH Clinical Center.
The Grant Perry Memorial Library is located at MTPPI’s Louisville, Kentucky office. To schedule a visit, please email [email protected]
Researcher Spotlight:

Dr. Yi Zhang
Dr. Zhang is a Senior Research Associate at MTPPI. She has extensive experience in healthcare and biostatistical research, designing and conducting studies using large administrative databases. Dr. Zhang is an expert at using advanced statistical techniques known as Causal Inference methods (Marginal Structural Models, g estimator and dynamic treatment regimes). She has spent the last 10 years working on applying causal inference modeling to studies of chronic health conditions and has received national acclaim for her work in the area of anemia management for dialysis patients. Dr. Zhang is the Principal Investigator of several projects advancing method approaches to using causal modeling and is the lead organizer of the CIMPOD Conference series.